Dnmt3btm3Enl
Targeted Allele Detail
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| Symbol: |
Dnmt3btm3Enl |
| Name: |
DNA methyltransferase 3B; targeted mutation 3, En Li |
| MGI ID: |
MGI:2182414 |
| Gene: |
Dnmt3b Location: Chr2:153491370-153529650 bp, + strand Genetic Position: Chr2, 75.79 cM, cytoband A2-A3
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| Alliance: |
Dnmt3btm3Enl page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:58298
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| Parent Cell Line: |
J1 (ES Cell)
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| Strain of Origin: |
129S4/SvJae
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Targeting took place in J1 ES cells homozygous for Dnmt3atm1Enl and heterozygous for Dnmt3btm4Enl. A 2.4kb region encoding the PC and ENV motifs was replaced with a puromycin selection cassette.
(J:58298)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Dnmt3b Mutation: |
52 strains or lines available
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| Original: |
J:58298 Okano M, et al., DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell. 1999 Oct 29;99(3):247-57 |
| All: |
1 reference(s) |
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Analysis Tools
