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Gene Expression Data
Assay Details
Assay
Reference: J:77124 Shinozaki K, et al., Absence of Cajal-Retzius cells and subplate neurons associated with defects of tangential cell migration from ganglionic eminence in Emx1/2 double mutant cerebral cortex. Development. 2002 Jul;129(14):3479-92
Assay type: RNA in situ
MGI Accession ID: MGI:2182380
Gene symbol: Reln
Gene name: reelin
Probe: Reln probe6
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 9A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebral cortex marginal layer Present Single cells 9A Expression is in the Cajal-Retzius cells.
Specimen 9B: embryonic day 13.5; Emx2tm1Sia/Emx2tm1Sia (more )
Structure Level Pattern Image Note
TS21: cerebral cortex marginal layer Present Single cells 9B Expression is in the Cajal-Retzius cells. The cells are fewer in number in this mutant.
Specimen 9C: embryonic day 13.5; Emx1tm1Sia/Emx1tm1Sia, Emx2tm1Sia/Emx2tm1Sia (more )
Structure Level Pattern Image Note
TS21: cerebral cortex Absent 9C
Specimen 9D,G: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cerebral cortex marginal layer Present Single cells 9D , 9G Expression is in the Cajal-Retzius cells.
Specimen 9E,H: embryonic day 15.5; Emx2tm1Sia/Emx2tm1Sia (more )
Structure Level Pattern Image Note
TS23: cerebral cortex marginal layer Present Single cells 9E , 9H Expression is in the Cajal-Retzius cells. The cells are absent from the neocortex and paleocortex regions, but are present in the most medial regions.
Specimen 9F,I: embryonic day 15.5; Emx1tm1Sia/Emx1tm1Sia, Emx2tm1Sia/Emx2tm1Sia (more )
Structure Level Pattern Image Note
TS23: cerebral cortex Absent 9F , 9I
Specimen 11J: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: telencephalon Present Single cells 11J Expression is in the pioneer neurons of the preplate.
Specimen 11K: embryonic day 11.5; Emx2tm1Sia/Emx2tm1Sia (more )
Structure Level Pattern Image Note
TS19: telencephalon Present Single cells 11K Expression is in the pioneer neurons of the preplate. Expression in this mutant is the same as in wild-type embryos.
Specimen 11L: embryonic day 11.5; Emx1tm1Sia/Emx1tm1Sia, Emx2tm1Sia/Emx2tm1Sia (more )
Structure Level Pattern Image Note
TS19: telencephalon Absent 11L
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory