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Foxj1tm1Bph
Targeted Allele Detail
Summary
Symbol: Foxj1tm1Bph
Name: forkhead box J1; targeted mutation 1, Brian P Hackett
MGI ID: MGI:2181746
Synonyms: hfh-4-
Gene: Foxj1  Location: Chr11:116221530-116226225 bp, - strand  Genetic Position: Chr11, 81.16 cM
Alliance: Foxj1tm1Bph page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:50025
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 1 was replaced with a PGK-neo cassette via homologous recombination. Lack of gene expression in tissues of homozygous mutant animals was confirmed by Northern blot, RT-PCR and in situ hybridization. (J:50025)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 31 assay results
In Structures Affected by this Mutation: 9 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Foxj1 Mutation:  20 strains or lines available
References
Original:  J:50025 Chen J, et al., Mutation of the mouse hepatocyte nuclear factor/forkhead homologue 4 gene results in an absence of cilia and random left-right asymmetry. J Clin Invest. 1998 Sep 15;102(6):1077-82
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory