Gene Expression Data
Assay Details
Assay
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Reference:
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J:75947
van den Akker E, et al., Cdx1 and Cdx2 have overlapping functions in anteroposterior patterning and posterior axis elongation. Development. 2002 May;129(9):2181-93
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:2180356
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Gene symbol:
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T
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Gene name:
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brachyury, T-box transcription factor T
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Probe:
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T cDNA4
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Visualized with:
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Alkaline phosphatase
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Results
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Specimen
9 cdx1 +/-:
embryonic day 8.5; Cdx1tm1Pgr/Cdx1 +
(more )
Note: 13 somites.
Specimen
9 cdx1 +/-:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
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Mutant Allele(s):
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Cdx1tm1Pgr/Cdx1+
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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13 somites.
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Specimen
9 cdx1 -/- cdx2+/-:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
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Mutant Allele(s):
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Cdx1tm1Pgr/Cdx1tm1Pgr Cdx2tm1Fbe/Cdx2+
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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15 somites.
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Structure |
Level |
Pattern |
Image |
Note |
TS13: trunk unsegmented mesenchyme |
Present |
Regionally restricted |
9_cdx1 -/- cdx2 +/-
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As in controls, the anterior boundary of expression was located one somite posterior to the last formed somite. The level was not changed in the mutant. The expression domain was posteriorly truncated due to loss of tail bud tissues in the mutant.
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