Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Galttm1Sgl
Name:	galactose-1-phosphate uridyl transferase; targeted mutation 1, Stanton Segal
MGI ID:	MGI:2180188
Synonyms:	G
Gene:	Galt  Location: Chr4:41755228-41758695 bp, + strand  Genetic Position: Chr4, 22.07 cM
Alliance:	Galttm1Sgl page

Germline Transmission:	Earliest citation of germline transmission: J:37472
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A HPRT cassette was used to replace a 700 nucleotide region containing exons 6, which encodes the catalytic site, 7, and 8. Enzyme activity in the livers of homozygous mutant mice was undetectable. (J:37472)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Galt Mutation:	15 strains or lines available

Original:	J:37472 Leslie ND, et al., A mouse model of galactose-1-phosphate uridyl transferase deficiency. Biochem Mol Med. 1996 Oct;59(1):7-12
All:	5 reference(s)