Summary | Mutation origin | Mutation description | Expression | Phenotypes | Tumor data | Find Mice (IMSR) | References

Symbol:	Ptgfrtm1Sna
Name:	prostaglandin F receptor; targeted mutation 1, Shuh Narumiya
MGI ID:	MGI:2179271
Synonyms:	FP, FP-, PGF2alpha, Ptgfrtm1Aic
Gene:	Ptgfr  Location: Chr3:151504247-151543165 bp, - strand  Genetic Position: Chr3, 76.96 cM
Alliance:	Ptgfrtm1Sna page

Germline Transmission:	Earliest citation of germline transmission: J:42113
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 2 was replaced with a lacZneo cassette via homologous recombination. X-gal staining was observed in ovaries of homozygous mutant animals and absence of gene expression in was verified via Northern blot analysis and radioligand binding assay. (J:42113)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	12 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

List all tumor models in MMHCdb carrying Ptgfrtm1Sna

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ptgfr Mutation:	23 strains or lines available

Original:	J:42113 Sugimoto Y, et al., Failure of parturition in mice lacking the prostaglandin F receptor. Science. 1997 Aug 1;277(5326):681-3
All:	24 reference(s)