Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Socs1tm2Wehi
Name:	suppressor of cytokine signaling 1; targeted mutation 2, Walter and Eliza Hall Institute of Medical Research
MGI ID:	MGI:2177057
Synonyms:	SOCS-1delta
Gene:	Socs1  Location: Chr16:10601672-10603400 bp, - strand  Genetic Position: Chr16, 5.81 cM
Alliance:	Socs1tm2Wehi page

Germline Transmission:	Earliest citation of germline transmission: J:72528
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6

Allele Type:    Targeted (Null/knockout) Mutation:    Disruption caused by insertion of vector   Mutation details: Homologous recombination is used to generate an allele where only the SOCS box of the gene is deleted. (J:72528)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

8 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Socs1 Mutation:	29 strains or lines available

Original:	J:72528 Zhang JG, et al., The SOCS box of suppressor of cytokine signaling-1 is important for inhibition of cytokine action invivo. Proc Natl Acad Sci U S A. 2001 Nov 6;98(23):13261-5
All:	1 reference(s)