Summary | Mutation origin | Mutation description | Expression | Recombinase activity | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Meox2tm1(cre)Sor
Name:	mesenchyme homeobox 2; targeted mutation 1, Philippe Soriano
MGI ID:	MGI:2176174
Synonyms:	Meox2Cre, Meox2-Cre, Meox2CreSor, MORE, More-cre, Mox2Cre, Mox2Cre, Mox2 Cre, Mox2-Cre, MoxCre
Gene:	Meox2  Location: Chr12:37158539-37229533 bp, + strand  Genetic Position: Chr12, 16.84 cM
Alliance:	Meox2tm1(cre)Sor page

Germline Transmission:	Earliest citation of germline transmission: J:60933
Parent Cell Line:	AK7 (ES Cell)
Strain of Origin:	129S4/SvJaeSor

Allele Type:    Targeted (Recombinase) Mutation:    Insertion   Meox2tm1(cre)Sor expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Meox2 (MGI:103219)   Mutation details: An nls-cre gene was inserted at the initiator ATG of the gene, followed by a neomycin selection cassette. The endogenous regulatory sequences drive expression by E5 in the epiblast and by E7 expression is detectable in all primitive ectoderm but not endoderm or trophectoderm. (J:60933, J:105278, J:132360)

Activity:	Tissue activity of this recombinase allele
Driver:	Meox2 (mouse) Summary of all recombinase alleles driven by Meox2. Comparative matrix view of recombinase activities Alliance mouse Meox2 gene page

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

52055 assay results 5 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Meox2 Mutation:	18 strains or lines available

Original:	J:60933 Tallquist MD, et al., Epiblast-restricted Cre expression in MORE mice: a tool to distinguish embryonic vs. extra-embryonic gene function. Genesis. 2000 Feb;26(2):113-5
All:	305 reference(s)