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Gene Expression Data
Assay Details
Assay
Reference: J:73506 Lowe LA, et al., Genetic dissection of nodal function in patterning the mouse embryo. Development. 2001 May;128(10):1831-43
Assay type: RNA in situ
MGI Accession ID: MGI:2159436
Gene symbol: Tcf15
Gene name: transcription factor 15
Probe: Paraxis probe5
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: Heterozygote Nodal mutants at E8.5 are defined as Type I, II or III mutants depending on the penetrance of the phenotype.
Results
Specimen 5. M.: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: head somite Present 5M Expression is detected in paired somites and the presomitic mesoderm.
TS13: trunk somite Present 5M Expression is detected in paired somites and the presomitic mesoderm.
TS13: trunk unsegmented mesenchyme Present 5M Expression is detected in paired somites and the presomitic mesoderm.
Specimen 5. N.: embryonic day 8.5; Nodaltm1Mku/Nodaltm1.1Mku (more )
Note: This is a type II mutant.
Structure Level Pattern Image Note
TS13: head somite Present 5N Expression is detected in paired somites.
TS13: trunk somite Present 5N Expression is detected in paired somites.
Specimen 5. O.: embryonic day 8.5; Nodaltm1Mku/Nodaltm1.1Mku (more )
Note: This is a type II mutant.
Structure Level Pattern Image Note
TS13: head somite Present 5O Expression is detected in the fused somites.
TS13: trunk somite Present 5O Expression is detected in the fused somites.
Specimen 5. P.: embryonic day 8.5; Nodaltm1Mku/Nodaltm1.1Mku (more )
Note: This is a type III mutant.
Structure Level Pattern Image Note
TS13: head somite Present 5P Expression is detected in paired somites.
TS13: trunk somite Present 5P Expression is detected in paired somites.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
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