Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Sema6aGt(KST069)Byg
Name:	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A; gene trap KST069, BayGenomics
MGI ID:	MGI:2156202
Synonyms:	Sema6aGt(pGT1TM)69Wcs, Sema6A KO
Gene:	Sema6a  Location: Chr18:47378321-47504267 bp, - strand  Genetic Position: Chr18, 25.08 cM, cytoband C
Alliance:	Sema6aGt(KST069)Byg page

Mutant Cell Line:	KST069
Germline Transmission:	Earliest citation of germline transmission: J:67920
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Gene trapped (Null/knockout, Reporter) Mutation:    Insertion of gene trap vector     Vector: pGT1TMpfs   Mutation details: A modified pGT1tm vector, pGT1TMpfs, was inserted at the codon for amino acid 473. This resulted in the complete abolition of transcription. (J:67920, J:70273) Inheritance:    Recessive Sequence Tags:  Sequence tag details (1 tag) Tag ID GenBank ID Method Tag Location (trapped strand)* Select KST069 CC156370 (MGI Seq Detail) 5' RACE Chr18:47403675-47403840 bp (+) * GRCm39 (strand of gene trap mutagenesis) Selected Tags: download BLAST at NCBI Genome Context:  Genome Browser view of this mutation 2 gene trap insertions have trapped this gene View all gene trap sequence tags in this region

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	12 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sema6a Mutation:	84 strains or lines available

Original:	J:67920 Leighton PA, et al., Defining brain wiring patterns and mechanisms through gene trapping in mice. Nature. 2001 Mar 8;410(6825):174-9
All:	30 reference(s)