Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Raxtm1Mjam
Name:	retina and anterior neural fold homeobox; targeted mutation 1, Milan Jamrich
MGI ID:	MGI:2152531
Synonyms:	Rx-
Gene:	Rax  Location: Chr18:66067710-66072160 bp, - strand  Genetic Position: Chr18, 39.03 cM
Alliance:	Raxtm1Mjam page

Germline Transmission:	Earliest citation of germline transmission: J:40830
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance cassette replaced a 2.7 kb region of the gene. The deleted region encodes the 5' portion of the transcript, corresponding to the protein initiation site and the N-terminal end of the homeodomain. (J:40830)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	46 assay results
In Structures Affected by this Mutation:	7 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rax Mutation:	16 strains or lines available

Original:	J:40830 Mathers PH, et al., The Rx homeobox gene is essential for vertebrate eye development. Nature. 1997 Jun 5;387(6633):603-7
All:	10 reference(s)