Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Il15tm1Imx
Name:	interleukin 15; targeted mutation 1, Immunex Research and Development Corporation
MGI ID:	MGI:2136897
Synonyms:	Il15-, IL-15-
Gene:	Il15  Location: Chr8:83058261-83129851 bp, - strand  Genetic Position: Chr8, 39.33 cM
Alliance:	Il15tm1Imx page

Germline Transmission:	Earliest citation of germline transmission: J:60915
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance cassette replaced 7.5kb of sequence containing exons 3-5, which encode amino acids 1-65. (J:60915)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 5 strains available      Cell Lines: 0 lines available
Carrying any Il15 Mutation:	43 strains or lines available

Original:	J:60915 Kennedy MK, et al., Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice [see comments]. J Exp Med. 2000 Mar 6;191(5):771-80
All:	203 reference(s)