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Gene Expression Data
Assay Details
Assay
Reference: J:59338 Clouthier DE, et al., Signaling pathways crucial for craniofacial development revealed by endothelin-A receptor-deficient mice. Dev Biol. 2000 Jan 1;217(1):10-24
Assay type: RNA in situ
MGI Accession ID: MGI:2135639
Gene symbol: Tfap2a
Gene name: transcription factor AP-2, alpha
Probe: Ap-2 probe6
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1B +/+: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: 1st branchial arch mesenchyme derived from neural crest Present 1B +/+
TS14: 2nd branchial arch mesenchyme derived from neural crest Present 1B +/+
TS14: rhombomere 1 Present Regionally restricted 1B +/+ Expression is in neural crest that is streaming into branchial arch 1.
TS14: rhombomere 2 Present Regionally restricted 1B +/+ Expression is in neural crest that is streaming into branchial arch 1.
TS14: rhombomere 4 Present Regionally restricted 1B +/+ Expression is in neural crest that is streaming into branchial arch 2.

Specimen 1B -/-: embryonic day 9.0; Ednratm1Ywa/Ednratm1Ywa (more )
Structure Level Pattern Image Note
TS14: 1st branchial arch mesenchyme derived from neural crest Present 1B -/- Expression in this mutant is the same as in wild-type embryos.
TS14: 2nd branchial arch mesenchyme derived from neural crest Present 1B -/- Expression in this mutant is the same as in wild-type embryos.
TS14: rhombomere 1 Present Regionally restricted 1B -/- Expression is in neural crest that is streaming into branchial arch 1. Expression in this mutant is the same as in wild-type embryos.
TS14: rhombomere 2 Present Regionally restricted 1B -/- Expression is in neural crest that is streaming into branchial arch 1. Expression in this mutant is the same as in wild-type embryos.
TS14: rhombomere 4 Present Regionally restricted 1B -/- Expression is in neural crest that is streaming into branchial arch 2. Expression in this mutant is the same as in wild-type embryos.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory