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Gene Expression Data
Assay Details
Assay
Reference: J:4384 Jowett AK, et al., Epithelial-mesenchymal interactions are required for msx 1 and msx 2 gene expression in the developing murine molar tooth. Development. 1993 Feb;117(2):461-70
Assay type: RNA in situ
MGI Accession ID: MGI:2135327
Gene symbol: Msx1
Gene name: msh homeobox 1
Probe: Msx1 cDNA2
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Assay notes: Probe was shortened by limited alkaline hydrolysis to around 100 bases.
Results
Specimen 1A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS18: 1st branchial arch mandibular component mesenchyme Present 1A Expression in the mesenchyme of the anterior region of both mandibular and maxillary processes with a decreasing gradient of expression away from the stomadeum. Expression in the mesenchyme adjacent to, and anterior to, an epitheliel thickening.
TS18: 1st branchial arch maxillary component mesenchyme Present 1A Expression in the mesenchyme of the anterior region of both mandibular and maxillary processes with a decreasing gradient of expression away from the stomadeum. Expression in the mesenchyme adjacent to, and anterior to, an epitheliel thickening.
TS18: 1st branchial groove Present Regionally restricted 1A Expression in the mesenchyme adjacent to the first branchial cleft.
TS18: 2nd branchial arch Weak Regionally restricted 1A Negligible expression in the anterior region of the second branchial arch.
TS18: 1st branchial arch mandibular component ectoderm Absent 1A
TS18: 1st branchial arch maxillary component ectoderm Absent 1A

Specimen 1C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: mandibular process mesenchyme Present Regionally restricted 1C Expression in the mesenchyme around the epithelial buds.
TS20: maxillary process mesenchyme Present Regionally restricted 1C Expression in the mesenchyme around the epithelial buds.

Specimen 2B: embryonic day 14.5 (more )
Note: Late cap stage molar.
Structure Level Pattern Image Note
TS22: lower jaw molar dental papilla Present 2B Expression in the dental papilla and dental follicle mesenchyme.
TS22: lower jaw molar dental follicle Present 2B Expression in the dental papilla and dental follicle mesenchyme.
TS22: lower jaw molar epithelium Absent 2B


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory