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Gene Expression Data
Assay Details
Assay
Reference: J:60975 Chang H, et al., Smad5 is essential for left-right asymmetry in mice. Dev Biol. 2000 Mar 1;219(1):71-8
Assay type: RNA in situ
MGI Accession ID: MGI:1891687
Gene symbol: Nodal
Gene name: nodal growth differentiation factor
Results
Specimen Table 1: embryonic day 8.0; Smad5tm1Zuk/Smad5tm1Zuk (more )
Note: 1-3 somites.
Structure Level Pattern Image Note
TS12: lateral plate mesoderm Present Expression is bilateral in 6 of 8 mutant embryos.

Specimen Table 1: embryonic day 8.0; Smad5tm1Zuk/Smad5tm1Zuk (more )
Note: 1-3 somites.
Structure Level Pattern Image Note
TS12: lateral plate mesoderm Absent Expression is absent in 2 of 8 mutant embryos.

Specimen Table 1: embryonic day 8.0; Smad5tm1Zuk/Smad5tm1Zuk (more )
Note: 4-5 somites.
Structure Level Pattern Image Note
TS12: lateral plate mesoderm Present Expression is bilateral in 1 of 4 mutant embryos.

Specimen Table 1: embryonic day 8.5; Smad5tm1Zuk/Smad5tm1Zuk (more )
Note: 4-5 somites.
Structure Level Pattern Image Note
TS12: lateral plate mesoderm Absent Expression is absent in 3 of 4 mutant embryos.

Specimen Table 1: embryonic day 8.5; Smad5tm1Zuk/Smad5tm1Zuk (more )
Note: 6-8 somites.
Structure Level Pattern Image Note
TS13: lateral plate mesoderm Absent Expression is absent in 5 of 5 mutant embryos.

Specimen not shown: embryonic day 7.5; Smad5tm1Zuk/Smad5tm1Zuk (more )
Structure Level Pattern Image Note
TS11: node Present

Specimen 3A: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: lateral plate mesoderm Present Regionally restricted 3A Expression is detected on the left side of the lateral plate mesoderm and both sides of the node however expression is stronger on the left side of the node.
TS12: primitive streak Present Regionally restricted 3A Expression is detected on the left side of the lateral plate mesoderm and both sides of the node however expression is stronger on the left side of the node.

Specimen 3B: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: lateral plate mesoderm Present Regionally restricted 3B Expression is detected on the left side of the lateral plate mesoderm and both sides of the node however expression is stronger on the left side of the node.
TS12: primitive streak Present Regionally restricted 3B Expression is detected on the left side of the lateral plate mesoderm and both sides of the node however expression is stronger on the left side of the node.

Specimen 3C: embryonic day 8.0; Smad5tm1Zuk/Smad5tm1Zuk (more )
Structure Level Pattern Image Note
TS12: lateral plate mesoderm Present 3C Expression is detected on the both sides of the lateral plate mesoderm and both sides of the node however expression is stronger on the left side of the node.
TS12: primitive streak Present 3C Expression is detected on the both sides of the lateral plate mesoderm and both sides of the node however expression is stronger on the left side of the node.

Specimen 3D: embryonic day 8.0; Smad5tm1Zuk/Smad5tm1Zuk (more )
Structure Level Pattern Image Note
TS12: lateral plate mesoderm Present 3D Expression is detected on the both sides of the lateral plate mesoderm and both sides of the node however expression is stronger on the left side of the node.
TS12: primitive streak Present 3D Expression is detected on the both sides of the lateral plate mesoderm and both sides of the node however expression is stronger on the left side of the node.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory