Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tapbptm1Luc
Name:	TAP binding protein; targeted mutation 1, Luc van Kaer
MGI ID:	MGI:1888941
Synonyms:	Tpn-
Gene:	Tapbp  Location: Chr17:34138452-34148264 bp, + strand  Genetic Position: Chr17, 17.98 cM
Alliance:	Tapbptm1Luc page

Germline Transmission:	Earliest citation of germline transmission: J:64177
Parent Cell Line:	TL1/TL-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion     Insertion of a neomycin resistance cassette into the fourth exon. (J:64177) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tapbp Mutation:	23 strains or lines available

Original:	J:64177 Grandea AG 3rd, et al., Impaired assembly yet normal trafficking of MHC class I molecules in Tapasin mutant mice. Immunity. 2000 Aug;13(2):213-22
All:	10 reference(s)