Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Dll1tm1Gos
Name:	delta like canonical Notch ligand 1; targeted mutation 1, Achim Gossler
MGI ID:	MGI:1861919
Synonyms:	Dll1-, Dll1lacZ
Gene:	Dll1  Location: Chr17:15587616-15597134 bp, - strand  Genetic Position: Chr17, 8.95 cM
Alliance:	Dll1tm1Gos page

Germline Transmission:	Earliest citation of germline transmission: J:39633
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: In-frame insertion of a LacZ-PGK-neomycin resistance cassette replaced sequences that code for amino acids 2-116 of the Dll1 gene. (J:39633)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	370 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	21 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Dll1 Mutation:	46 strains or lines available

Original:	J:39633 Hrabe de Angelis M, et al., Maintenance of somite borders in mice requires the Delta homologue DII1. Nature. 1997 Apr 17;386(6626):717-21
All:	58 reference(s)