Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Klf1Nan
Name:	Kruppel-like transcription factor 1 (erythroid); neonatal anemia
MGI ID:	MGI:1861107
Synonyms:	Nan
Gene:	Klf1  Location: Chr8:85628611-85631920 bp, + strand  Genetic Position: Chr8, 41.3 cM
Alliance:	Klf1Nan page

Strain of Origin:

PT x (C3H/HeH x 101/H)F1

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: An A-to-T transversion at base pair 1064 (reference sequence NM_010635) in exon 3 changes glutamic acid to aspartic acid (p.E339D) within the second zinc finger required for DNA binding in the encoded protein. (J:163685) Inheritance:    Semidominant

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	2 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Klf1 Mutation:	21 strains or lines available

Original:	J:13933 Lyon MF, et al., Dominant haemolytic anemia. Mouse News Lett. 1983;68:68
All:	11 reference(s)