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Fgf5tm1Mrt
Targeted Allele Detail
Summary
Symbol: Fgf5tm1Mrt
Name: fibroblast growth factor 5; targeted mutation 1, Gail R Martin
MGI ID: MGI:1857847
Synonyms: FGF-5-, Fgfneo
Gene: Fgf5  Location: Chr5:98402108-98424892 bp, + strand  Genetic Position: Chr5, 47.77 cM, cytoband E1-F
Alliance: Fgf5tm1Mrt page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:20551
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    Insertion of a neomycin cassette into exon 1. (J:20551)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fgf5 Mutation:  14 strains or lines available
Notes
This mutation produces abnormally long hair, the phenotype being very closely similar to that of Fgf5go homozygotes (angora, J:20551).
References
Original:  J:20551 Hebert JM, et al., FGF5 as a regulator of the hair growth cycle: evidence from targeted and spontaneous mutations. Cell. 1994 Sep 23;78(6):1017-25
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory