Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ntf3tm1Jae
Name:	neurotrophin 3; targeted mutation 1, Rudolf Jaenisch
MGI ID:	MGI:1857232
Synonyms:	NT-3-, NT3-
Gene:	Ntf3  Location: Chr6:126078375-126143703 bp, - strand  Genetic Position: Chr6, 60.45 cM
Alliance:	Ntf3tm1Jae page

Germline Transmission:	Earliest citation of germline transmission: J:23882
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     The entire coding region for the Ntf3 gene was replaced by a neomycin cassette. (J:23882)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	82 assay results
In Structures Affected by this Mutation:	13 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Ntf3 Mutation:	24 strains or lines available

Original:	J:23882 Ernfors P, et al., Lack of neurotrophin-3 leads to deficiencies in the peripheral nervous system and loss of limb proprioceptive afferents. Cell. 1994 May 20;77(4):503-12
All:	47 reference(s)