Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tubtm1Rok
Name:	TUB bipartite transcription factor; targeted mutation 1, Rosana Kapeller
MGI ID:	MGI:1857081
Synonyms:	tub-
Gene:	Tub  Location: Chr7:108610087-108633666 bp, + strand  Genetic Position: Chr7, 57.21 cM
Alliance:	Tubtm1Rok page

Germline Transmission:	Earliest citation of germline transmission: J:59994
Parent Cell Line:	MPI-71.6 (ES Cell)
Strain of Origin:	B6.129P2-Hprt1b-m3

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     A neomycin resistance cassette replaced 16 kb of sequence spanning exons 1-8. (J:59994) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tub Mutation:	36 strains or lines available

Original:	J:59994 Stubdal H, et al., Targeted deletion of the tub mouse obesity gene reveals that tubby is a loss-of-function mutation. Mol Cell Biol. 2000 Feb;20(3):878-82
All:	2 reference(s)