As Radiation induced Allele Detail MGI Mouse (MGI:1855934)

As
Radiation induced Allele Detail

Summary

Symbol:	As
Name:	agouti suppressor
MGI ID:	MGI:1855934
Synonyms:	As, A^s, In(1)2H
Gene:	As Location: unknown Genetic Position: Chr2, Syntenic
Alliance:	As page

Mutation
origin

Strain of Origin:

(C3H/HeH x 101/H)F1

Mutation
description

Allele Type:		Radiation induced
Mutation:		Inversion
		As involves 1 genes/genome features (As) View all
		Mutation details: As is associated with a long inversion, In(1)2H, which suppresses crossing over between Pldn and As and increases crossing-over between a and Gdf5. (J:13742)
Inheritance:		Semidominant

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any As Mutation:	0 strains or lines available

Notes

The effect in heterozygotes with other agouti-locus alleles (A^s A^w/+ x, where x = A^w, A, a^t, or a) is more pronounced in the pinna, tail, and hindfoot than in the body pelage (J:12033).

References

Original:	J:5027 Phillips RJS, A cis-trans position effect at the A locus of the house mouse. Genetics. 1966 Aug;54(2):485-95
All:	6 reference(s)

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