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Gene Expression Data
Assay Details
Assay
Reference: J:26753 Manley NR, et al., The role of Hoxa-3 in mouse thymus and thyroid development. Development. 1995 Jul;121(7):1989-2003
Assay type: RNA in situ
MGI Accession ID: MGI:1352828
Gene symbol: Hoxa3
Gene name: homeobox A3
Probe: Hoxa3 cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 2A The cranial limit of expression is at the rhombomere 4/5 boundary.
TS17: 3rd branchial pouch Present 2A
TS17: branchial arch Present Regionally restricted 2A The cranial limit of expression is at the level of branchial arch 3.
TS17: 3rd branchial arch mesenchyme derived from neural crest Present 2A

Specimen 2B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 3rd branchial arch mesenchyme Present 2B
TS17: 3rd branchial pouch endoderm Present 2B
TS17: 4th branchial arch mesenchyme Present 2B
TS17: 4th branchial pouch endoderm Present 2B

Specimen 7 +/- embryo: embryonic day 9.5; Hoxa3tm1Mrc/Hoxa3+ (more )
Structure Level Pattern Image Note
TS15: branchial arch Present Regionally restricted 7+/- The cranial limit of expression is in branchial arch 3.
TS15: future hindbrain Present Regionally restricted 7+/- The cranial limit of expression is in rhombomere 5.
TS15: trunk somite Present 7+/-

Specimen 7 -/- embryo: embryonic day 9.5; Hoxa3tm1Mrc/Hoxa3tm1Mrc (more )
Structure Level Pattern Image Note
TS15: future hindbrain Present Regionally restricted 7-/- The cranial limit of expression is in rhombomere 5. Expression in the homozygous and the heterozygous embryos are the same.
TS15: branchial arch Present Regionally restricted 7-/- The cranial level of expression is in branchial arch 3. Expression in the homozygous and the heterozygous embryos are the same.
TS15: trunk somite Present Regionally restricted 7-/- Expression in the homozygous and the heterozygous embryos are the same.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory