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Gene Expression Data
Assay Details
Assay
Reference: J:56972 Constam DB, et al., Tissue-specific requirements for the proprotein convertase furin/SPC1 during embryonic turning and heart looping. Development. 2000 Jan;127(2):245-54
Assay type: RNA in situ
MGI Accession ID: MGI:1351505
Gene symbol: Pitx2
Gene name: paired-like homeodomain transcription factor 2
Probe: Pitx2 cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1A -/-: embryonic day 8.5; Furintm1Ajmr/Furintm1Ajmr (more )
Structure Level Pattern Image Note
TS28: placenta Present 1A -/- Expression in the mutant is higher than in wild-type.
TS11: extraembryonic mesenchyme Present Regionally restricted 1A -/- Expression detected in the lateral plate mesoderm. Expression in the mutant is higher than in wild-type
Specimen 1A WT: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS28: placenta Present 1A WT Expression in the mutant is higher then in wild-type.
TS11: extraembryonic mesenchyme Present Regionally restricted 1A WT Expression detected in the lateral plate mesoderm. Expression in the mutant is higher then in wild-type
Specimen 1B WT: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS11: extraembryonic mesenchyme Present Regionally restricted 1B WT Expression is detected in the left lateral plate mesoderm.
Specimen 1B -/-: embryonic day 8.5; Furintm1Ajmr/Furintm1Ajmr (more )
Structure Level Pattern Image Note
TS11: extraembryonic mesenchyme Present Regionally restricted 1B -/- In some cases expression is only in the left lateral plate mesoderm and in other cases it is bilateral.
Specimen 1C: embryonic day 8.5; Furintm1Ajmr/Furintm1Ajmr (more )
Structure Level Pattern Image Note
TS11: extraembryonic mesenchyme Present 1C Expression detected in the lateral plate mesoderm.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory