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Gene Expression Data
Assay Details
Assay
Reference: J:41540 Rossel M, et al., Mice mutant for both Hoxa1 and Hoxb1 show extensive remodeling of the hindbrain and defects in craniofacial development. Development. 1999 Nov;126(22):5027-40
Assay type: RNA in situ
MGI Accession ID: MGI:1346697
Gene symbol: Egr2
Gene name: early growth response 2
Probe: Krox-20 probe8
Probe preparation: RNA
Results
Specimen 4A: embryonic day 8.5; Hoxa1tm1Mrc/Hoxa1+, Hoxb1tm3Mrc/Hoxb1+ (more )
Note: 4-9 somites. Also stained for Mafb (assay MGI:1346698).
Structure Level Pattern Image Note
TS13: rhombomere 3 Present 4A

Specimen 4B: embryonic day 8.5; Hoxa1tm1Mrc/Hoxa1tm1Mrc (more )
Note: 4-9 somites. Also stained for Mafb (assay MGI:1346698).
Structure Level Pattern Image Note
TS13: future hindbrain Present Spotted 4B Expression is patchy and extends much more caudally than normal in this mutant.

Specimen 4C: embryonic day 8.5; Hoxa1tm1Mrc/Hoxa1tm1Mrc, Hoxb1tm3Mrc/Hoxb1+ (more )
Note: 4-9 somites. Also stained for Mafb (assay MGI:1346698).
Structure Level Pattern Image Note
TS13: future hindbrain Present Spotted 4C Expression is patchy and extends much more caudally than normal in this mutant.

Specimen 4D: embryonic day 8.5; Hoxa1tm1Mrc/Hoxa1tm1Mrc, Hoxb1tm3Mrc/Hoxb1tm3Mrc (more )
Note: 4-9 somites. Also stained for Mafb (assay MGI:1346698).
Structure Level Pattern Image Note
TS13: future hindbrain Present Spotted 4D Expression is patchy and extends much more caudally than normal in this mutant.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory