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Gene Expression Data
Assay Details
Assay
Reference: J:41540 Rossel M, et al., Mice mutant for both Hoxa1 and Hoxb1 show extensive remodeling of the hindbrain and defects in craniofacial development. Development. 1999 Nov;126(22):5027-40
Assay type: RNA in situ
MGI Accession ID: MGI:1346698
Gene symbol: Mafb
Gene name: MAF bZIP transcription factor B
Probe: kreisler probe2
Probe preparation: RNA
Results
Specimen 4A: embryonic day 8.5; Hoxa1tm1Mrc/Hoxa1+, Hoxb1tm3Mrc/Hoxb1+ (more )
Note: 4-9 somites. Also stained for Egr2 (assay MGI:1346697).
Structure Level Pattern Image Note
TS13: rhombomere 5 Present 4A
TS13: future hindbrain posterior to rhombomere 5 Present Regionally restricted 4A Expression is present in rhombomere 6.
Specimen 4B: embryonic day 8.5; Hoxa1tm1Mrc/Hoxa1tm1Mrc (more )
Note: 4-9 somites. Also stained for Egr2 (assay MGI:1346697).
Structure Level Pattern Image Note
TS13: future hindbrain posterior to rhombomere 5 Present Regionally restricted 4B Expression is restricted to rhombomere 6 in this mutant.
Specimen 4C: embryonic day 8.5; Hoxa1tm1Mrc/Hoxa1tm1Mrc, Hoxb1tm3Mrc/Hoxb1+ (more )
Note: 4-9 somites. Also stained for Egr2 (assay MGI:1346697).
Structure Level Pattern Image Note
TS13: future hindbrain posterior to rhombomere 5 Present Regionally restricted 4C Expression is restricted to rhombomere 6 in this mutant.
Specimen 4D: embryonic day 8.5; Hoxa1tm1Mrc/Hoxa1tm1Mrc, Hoxb1tm3Mrc/Hoxb1tm3Mrc (more )
Note: 4-9 somites. Also stained for Egr2 (assay MGI:1346697).
Structure Level Pattern Image Note
TS13: future hindbrain posterior to rhombomere 5 Present Regionally restricted 4D Expression is restricted to rhombomere 6 in this mutant.
Specimen 4E: embryonic day 8.5; Hoxa1tm1Mrc/Hoxa1+, Hoxb1tm3Mrc/Hoxb1+ (more )
Note: 4-9 somites. Double labeled: purple - Mafb; red/brown - Egr2 (assay MGI:1346699).
Structure Level Pattern Image Note
TS13: rhombomere 5 Present 4E
TS13: future hindbrain posterior to rhombomere 5 Present Regionally restricted 4E Expression is present in rhombomere 6.
Specimen 4F: embryonic day 8.5; Hoxa1tm1Mrc/Hoxa1tm1Mrc, Hoxb1tm3Mrc/Hoxb1tm3Mrc (more )
Note: 4-9 somites. Double labeled: purple - Mafb; red/brown - Egr2 (assay MGI:1346699). (G) Higher magnification of the embryo shown in (F).
Structure Level Pattern Image Note
TS13: future hindbrain posterior to rhombomere 5 Present Regionally restricted 4F , 4G Expression is restricted to rhombomere 6 in this mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory