Gene Expression Data
Assay Details
Assay
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Reference:
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J:50462
Dassule HR, et al., Analysis of epithelial-mesenchymal interactions in the initial morphogenesis of the mammalian tooth. Dev Biol. 1998 Oct 15;202(2):215-27
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:1340494
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Gene symbol:
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Bmp2
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Gene name:
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bone morphogenetic protein 2
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Results
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Specimen
1C:
embryonic day 11.0
(more )
Specimen
1C:
(close )
Genetic Background:
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Swiss Webster
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Age:
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embryonic day 11.0
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Structure |
Level |
Pattern |
Image |
Note |
TS18: 1st branchial arch mandibular component |
Weak |
Regionally restricted |
1C
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Bmp2 is expressed at the mesial tip of the jaw in a short, thin strip of epithelial cells that extends distally. In all cases, expression was symmetrical on either side of the median sulcus.
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TS18: tongue |
Absent |
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1C
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Specimen
1I:
embryonic day 11.5
(more )
Specimen
1I:
(close )
Genetic Background:
|
Swiss Webster
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Age:
|
embryonic day 11.5
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Sex:
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Not Specified
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Type:
|
whole mount
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Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS19: mandible primordium |
Strong |
Regionally restricted |
1I
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The midline expression extends further distally. Expression is upregulated relative to E11.0. Highest levels of expression are mesially and distally with an apparent downregulation in between.
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TS19: tongue |
Absent |
|
1I
|
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Specimen
1O:
embryonic day 12.0
(more )
Specimen
1O:
(close )
Genetic Background:
|
Swiss Webster
|
Age:
|
embryonic day 12.0
|
Sex:
|
Not Specified
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Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: mandible primordium |
Present |
Regionally restricted |
1O
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Expression is completely downregulated in the diastema. Expression occurs at the midline in the incisor domains and further distally in the molar primordia. Bmp2 is also expressed in the most distal mesenchyme of the outgrowing jaw.
|
TS20: tongue |
Absent |
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1O
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Specimen
1U:
embryonic day 12.0
(more )
Specimen
1U:
(close )
Genetic Background:
|
Swiss Webster
|
Age:
|
embryonic day 12.0
|
Sex:
|
Not Specified
|
Type:
|
section
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Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: mandible primordium |
Strong |
Regionally restricted |
1U
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Bmp2 is expressed at the tip of the tooth epithelium.
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