Gene Expression Data
Assay Details
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Assay
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Reference:
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J:38384
Arkell R, et al., BMP-7 influences pattern and growth of the developing hindbrain of mouse embryos. Development. 1997 Jan;124(1):1-12
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:1332536
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Gene symbol:
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Bmp7
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Gene name:
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bone morphogenetic protein 7
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Results
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Specimen
1A:
embryonic day 6.5
(more )
Note: Early streak.
Specimen
1A:
(close )
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Genetic Background:
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(C57BL/6 x DBA)F1
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Age:
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embryonic day 6.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Note:
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Early streak.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS9: primitive streak |
Present |
Regionally restricted |
1A
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BMP-7 transcripts are detected at the anterior end of the primitive streak.
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Specimen
1B:
embryonic day 7.0
(more )
Note: Late streak.
Specimen
1B:
(close )
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Genetic Background:
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(C57BL/6 x DBA)F1
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Age:
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embryonic day 7.0
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Note:
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Late streak.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS10: embryo mesoderm |
Present |
Regionally restricted |
1B
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BMP-7 mRNA is localized to the rostral third of the primitive streak, the node and to the axial mesoderm emanating from the node.
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| TS10: node |
Present |
Regionally restricted |
1B
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BMP-7 mRNA is localized to the rostral third of the primitive streak, the node and to the axial mesoderm emanating from the node.
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| TS10: primitive streak |
Present |
Regionally restricted |
1B
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BMP-7 mRNA is localized to the rostral third of the primitive streak, the node and to the axial mesoderm emanating from the node.
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Specimen
1C:
embryonic day 7.0
(more )
Note: Early allantoic bud stage.
Specimen
1C:
(close )
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Genetic Background:
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(C57BL/6 x DBA)F1
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Age:
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embryonic day 7.0
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Note:
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Early allantoic bud stage.
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Specimen
1D:
embryonic day 7.5
(more )
Note: Early headfold.
Specimen
1D:
(close )
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Genetic Background:
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(C57BL/6 x DBA)F1
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Age:
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embryonic day 7.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Note:
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Early headfold.
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Specimen
1E:
embryonic day 7.5
(more )
Note: Headfold, presomite stage.
Specimen
1E:
(close )
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Genetic Background:
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(C57BL/6 x DBA)F1
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Age:
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embryonic day 7.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Note:
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Headfold, presomite stage.
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Specimen
1F:
embryonic day 7.0
(more )
Note: Allantoic bud stage.
Specimen
1F:
(close )
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Genetic Background:
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(C57BL/6 x DBA)F1
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Age:
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embryonic day 7.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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Allantoic bud stage.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS10: embryo mesoderm |
Present |
Regionally restricted |
1F
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Transcripts can be seen in both the lateral and axial mesoderm.
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Specimen
1G:
embryonic day 7.5
(more )
Note: Headfold, presomite stage embryo.
Specimen
1G:
(close )
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Genetic Background:
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(C57BL/6 x DBA)F1
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Age:
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embryonic day 7.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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Headfold, presomite stage embryo.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS11: embryo mesoderm |
Present |
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1G
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| TS11: neural ectoderm |
Present |
Regionally restricted |
1G
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BMP-7 transcripts are seen in the ventral neurectoderm, but not in the dorsal neurectoderm.
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| TS11: surface ectoderm |
Strong |
Regionally restricted |
1G
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Transcripts accumulate in the surface ectoderm of the anterior and posterior regions of the embryo.
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Specimen
1H:
embryonic day 9.0
(more )
Note: 14-somite embryo.
Specimen
1H:
(close )
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Genetic Background:
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(C57BL/6 x DBA)F1
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Age:
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embryonic day 9.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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14-somite embryo.
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Specimen
not shown:
embryonic day 8.0
(more )
Note: 6-somite embryo.
Specimen
not shown:
(close )
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Genetic Background:
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(C57BL/6 x DBA)F1
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Age:
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embryonic day 8.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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6-somite embryo.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS12: embryo mesenchyme |
Present |
Regionally restricted |
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BMP-7 is only detected in sections up to 105 um behind the rostral extent of the axial mesoderm. Transcripts are no longer seen in the mesoderm adjacent to the hindbrain region.
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Specimen
not shown:
embryonic day 8.5
(more )
Note: 12-somite embryo.
Specimen
not shown:
(close )
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Genetic Background:
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(C57BL/6 x DBA)F1
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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12-somite embryo.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: embryo mesenchyme |
Present |
Regionally restricted |
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BMP-7 expression is only detected in sections up to 140 um behind the rostral extent of the axial mesoderm.
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Specimen
1I:
embryonic day 8.0
(more )
Note: 6-somite embryo.
Specimen
1I:
(close )
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Genetic Background:
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(C57BL/6 x DBA)F1
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Age:
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embryonic day 8.0
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Note:
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6-somite embryo.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS12: neural ectoderm |
Present |
Regionally restricted |
1I
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The ventral expression of BMP-7 is most obvious in neurectoderm extending from the anterior of the midbrain to the preotic sulcus and is present up to the preotic sulcus.
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| TS12: optic sulcus neural ectoderm |
Present |
Regionally restricted |
1I
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The ventral expression of BMP-7 is most obvious in neurectoderm extending from the anterior of the midbrain to the preotic sulcus and is present up to the preotic sulcus.
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| TS12: future spinal cord neural plate |
Present |
Regionally restricted |
1I
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Transcripts are found in the midline of the neural plate in two regions: a region of higher signal extends from the anterior limit of the midbrain to the preotic sulcus; a lower level of signal extends from the preotic sulcus to the otic sulcus.
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Specimen
1J:
embryonic day 8.5
(more )
Note: 10-somite embryo.
Specimen
1J:
(close )
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Genetic Background:
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(C57BL/6 x DBA)F1
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Note:
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10-somite embryo.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: future midbrain |
Present |
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1J
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The ventral neurectoderm expression is now essentially confined to the midbrain.
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Specimen
1K:
embryonic day 9.0
(more )
Note: 16-somite embryo.
Specimen
1K:
(close )
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Genetic Background:
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(C57BL/6 x DBA)F1
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Age:
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embryonic day 9.0
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Note:
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16-somite embryo.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS14: embryo ectoderm |
Present |
Regionally restricted |
1K
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The ventral neurectoderm of the midbrain and rostral diencephalon contains BMP-7 transcripts as does the dorsal-most neurectoderm in the anterior cranial region.
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| TS14: future diencephalon |
Present |
Regionally restricted |
1K
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The ventral neurectoderm of the midbrain and rostral diencephalon contains BMP-7 transcripts as does the dorsal-most neurectoderm in the anterior cranial region.
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| TS14: future midbrain |
Present |
Regionally restricted |
1K
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The ventral neurectoderm of the midbrain and rostral diencephalon contains BMP-7 transcripts as does the dorsal-most neurectoderm in the anterior cranial region.
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Specimen
not shown:
embryonic day 9.0
(more )
Note: 18-somite embryo.
Specimen
not shown:
(close )
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Genetic Background:
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(C57BL/6 x DBA)F1
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Age:
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embryonic day 9.0
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Note:
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18-somite embryo.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS14: future midbrain |
Present |
Regionally restricted |
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By the 18-somite stage, the diencephalic expression disappears and ventral transcription is again seen only in the midbrain.
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| TS14: future diencephalon |
Absent |
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By the 18-somite stage, the diencephalic expression disappears and ventral transcription is again seen only in the midbrain.
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