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Gene Expression Data
Assay Details
Assay
Reference: J:50401 Bel S, et al., Genetic interactions and dosage effects of Polycomb group genes in mice. Development. 1998 Sep;125(18):3543-51
Assay type: RNA in situ
MGI Accession ID: MGI:1331670
Gene symbol: Hoxc8
Gene name: homeobox C8
Probe: Hoxc8 probe4
Probe preparation: labelled with digoxigenin RNA
Results
Specimen 4A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: tail paraxial mesenchyme Present Regionally restricted 4A The normal boundary is pv12 in the mesoderm.
Specimen not shown: embryonic day 12.5; Cbx2tm1Cim/Cbx2tm1Cim (more )
Structure Level Pattern Image Note
TS20: tail paraxial mesenchyme Present Regionally restricted There is a 1-somite anterior shift in expression.
Specimen 4B: embryonic day 12.5; Bmi1tm1Brn/Bmi1+, Cbx2tm1Cim/Cbx2+ (more )
Structure Level Pattern Image Note
TS20: tail paraxial mesenchyme Weak Regionally restricted 4B A weak signal is detected in pv11.
Specimen 4C: embryonic day 12.5; Bmi1tm1Brn/Bmi1tm1Brn, Cbx2tm1Cim/Cbx2+ (more )
Structure Level Pattern Image Note
TS20: tail paraxial mesenchyme Present Regionally restricted 4C The compound M33+/-bmi1-/- presents the same limit as bmi1-/-, up to pv11.
Specimen 4D: embryonic day 12.5; Bmi1tm1Brn/Bmi1+, Cbx2tm1Cim/Cbx2tm1Cim (more )
Structure Level Pattern Image Note
TS20: tail paraxial mesenchyme Present Regionally restricted 4D The compound M33-/-bmi1+/- presents a progressive shift compared to the single mutant M33-/-, up to pv10.
Specimen 4E: embryonic day 12.5; Bmi1tm1Brn/Bmi1tm1Brn, Cbx2tm1Cim/Cbx2tm1Cim (more )
Structure Level Pattern Image Note
TS20: tail paraxial mesenchyme Present Regionally restricted 4E An extended anterior shift is detected in the double mutant embryos, compared to the wild type, i.e. up to pv9.
Specimen 4F: embryonic day 12.5; Bmi1tm1Brn/Bmi1tm1Brn, Cbx2tm1Cim/Cbx2tm1Cim (more )
Structure Level Pattern Image Note
TS20: tail paraxial mesenchyme Present Regionally restricted 4F An extended anterior shift is detected in the double mutant embryos, compared to the wild type, i.e. up to pv9.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
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