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Gene Expression Data
Assay Details
Assay
Reference: J:50401 Bel S, et al., Genetic interactions and dosage effects of Polycomb group genes in mice. Development. 1998 Sep;125(18):3543-51
Assay type: RNA in situ
MGI Accession ID: MGI:1331667
Gene symbol: Hoxc9
Gene name: homeobox C9
Probe: Hoxc9 probe2
Probe preparation: labelled with digoxigenin RNA
Results
Specimen 3A: embryonic day 9.5 (more )
Note: 28-30 somites.
Structure Level Pattern Image Note
TS15: neural tube Present Regionally restricted 3A Normal boundaries for Hoxc9 are s17/16 in the mesoderm and s10/9 in the neural tube.
TS15: trunk paraxial mesenchyme Present Regionally restricted 3A Normal boundaries for Hoxc9 are s17/16 in the mesoderm and s10/9 in the neural tube.

Specimen 3B: embryonic day 9.5; Bmi1tm1Brn/Bmi1+, Cbx2tm1Cim/Cbx2+ (more )
Note: 28-30 somites.
Structure Level Pattern Image Note
TS15: neural tube Present Regionally restricted 3B The boundary of expression is not affected in the trans-heterozygote embryos.
TS15: trunk paraxial mesenchyme Present Regionally restricted 3B The boundary of expression is not affected in the trans-heterozygote embryos.

Specimen 3C: embryonic day 9.5; Bmi1tm1Brn/Bmi1tm1Brn (more )
Note: 28-30 somites.
Structure Level Pattern Image Note
TS15: neural tube Present Regionally restricted 3C The boundary is shifted to pv15 in the mesoderm.
TS15: trunk paraxial mesenchyme Present Regionally restricted 3C The boundary is shifted to pv15 in the mesoderm.

Specimen 3D: embryonic day 9.5; Bmi1tm1Brn/Bmi1+, Cbx2tm1Cim/Cbx2tm1Cim (more )
Note: 28-30 somites.
Structure Level Pattern Image Note
TS15: neural tube Present Regionally restricted 3D The expression pattern is unaffected.
TS15: trunk paraxial mesenchyme Present Regionally restricted 3D The expression pattern is unaffected.

Specimen 3E: embryonic day 9.5; Bmi1tm1Brn/Bmi1tm1Brn, Cbx2tm1Cim/Cbx2+ (more )
Note: 28-30 somites.
Structure Level Pattern Image Note
TS15: neural tube Present Regionally restricted 3E A 1-segment anterior shift is detected up to pv15 in the paraxial mesoderm.
TS15: trunk paraxial mesenchyme Present Regionally restricted 3E A 1-segment anterior shift is detected up to pv15 in the paraxial mesoderm.

Specimen 3F: embryonic day 9.5; Bmi1tm1Brn/Bmi1tm1Brn, Cbx2tm1Cim/Cbx2tm1Cim (more )
Note: 28-30 somites.
Structure Level Pattern Image Note
TS15: neural tube Present Regionally restricted 3F The expression pattern of Hoxc9 is shifted anteriorly by 4 segments, up to pv11 in the somitic mesoderm while it is not affected in the neurectoderm.
TS15: trunk paraxial mesenchyme Present Regionally restricted 3F The expression pattern of Hoxc9 is shifted anteriorly by 4 segments, up to pv11 in the somitic mesoderm while it is not affected in the neurectoderm.

Specimen 3G: embryonic day 9.5 (more )
Note: 20-somites.
Structure Level Pattern Image Note
TS14: head paraxial mesenchyme Present Regionally restricted 3G
TS14: neural tube Present Regionally restricted 3G
TS14: optic vesicle neural ectoderm Present Regionally restricted 3G

Specimen 3H: embryonic day 9.5; Bmi1tm1Brn/Bmi1tm1Brn, Cbx2tm1Cim/Cbx2tm1Cim (more )
Note: 20-somites.
Structure Level Pattern Image Note
TS14: head paraxial mesenchyme Present Regionally restricted 3H An anterior shift is detected not only in the mesoderm but also in the neurectoderm.
TS14: neural tube Present Regionally restricted 3H An anterior shift is detected not only in the mesoderm but also in the neurectoderm.
TS14: optic vesicle neural ectoderm Present Regionally restricted 3H An anterior shift is detected not only in the mesoderm but also in the neurectoderm.

Specimen not shown: embryonic day 9.5; Cbx2tm1Cim/Cbx2tm1Cim (more )
Structure Level Pattern Image Note
TS15: neural tube Present Regionally restricted Boundaries for Hoxc9 are s17/16 in the mesoderm and s10/9 in the neural tube.
TS15: trunk paraxial mesenchyme Present Regionally restricted Boundaries for Hoxc9 are s17/16 in the mesoderm and s10/9 in the neural tube.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory