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Gene Expression Data
Assay Details
Assay
Reference: J:50582 Roebroek AJ, et al., Failure of ventral closure and axial rotation in embryos lacking the proprotein convertase Furin. Development. 1998 Dec;125(24):4863-76
Assay type: RNA in situ
MGI Accession ID: MGI:1331482
Gene symbol: Nkx2-5
Gene name: NK2 homeobox 5
Probe: Nkx2-5 probe2
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 7F WT: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: heart Present Regionally restricted 7F WT

Specimen 7F -/-: embryonic day 8.0; Furintm1Ajmr/Furintm1Ajmr (more )
Structure Level Pattern Image Note
TS12: heart Present Regionally restricted 7F -/- Expression is dramatically reduced in mutants.

Specimen 7G: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: heart Present Regionally restricted 7G

Specimen 7H: embryonic day 8.0; Furintm1Ajmr/Furintm1Ajmr (more )
Structure Level Pattern Image Note
TS12: heart Present Regionally restricted 7H Expression is dramatically reduced in mutants.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory