Gene Expression Data
Assay Details
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Assay
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Reference:
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J:49653
Yang Y, et al., Evidence that preaxial polydactyly in the Doublefoot mutant is due to ectopic Indian Hedgehog signaling. Development. 1998 Aug;125(16):3123-32
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:1331129
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Gene symbol:
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Bmp2
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Gene name:
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bone morphogenetic protein 2
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Probe:
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BMP2 cDNA
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
4A:
embryonic day 11.0
(more  )
Specimen
4A:
(close  )
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Genetic Background:
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involves: 101/H * C3H/HeH
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Age:
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embryonic day 11.0
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
4B:
embryonic day 11.0; Dbf/Dbf +
(more )
Specimen
4B:
(close )
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Genetic Background:
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involves: 101/H * C3H/HeH
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Mutant Allele(s):
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Dbf/Dbf+
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Age:
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embryonic day 11.0
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS18: forelimb bud |
Present |
Regionally restricted |
4B
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In Dbf heterozygous mutants, ectopic Bmp2 expression is detected in a broad band across the AP axis at the distal part of both the forelimb and hindlimb.
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Specimen
4C:
embryonic day 11.0
(more )
Specimen
4C:
(close )
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Genetic Background:
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involves: 101/H * C3H/HeH
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Age:
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embryonic day 11.0
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
4D:
embryonic day 11.0; Dbf/Dbf +
(more )
Specimen
4D:
(close )
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Genetic Background:
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involves: 101/H * C3H/HeH
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Mutant Allele(s):
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Dbf/Dbf+
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Age:
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embryonic day 11.0
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS18: hindlimb bud |
Present |
Regionally restricted |
4D
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In Dbf heterozygous mutants, ectopic Bmp2 expression is detected in a broad band across the AP axis at the distal part of both the forelimb and hindlimb.
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Specimen
4E:
embryonic day 11.5
(more )
Specimen
4E:
(close )
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Genetic Background:
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involves: 101/H * C3H/HeH
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: handplate |
Present |
Regionally restricted |
4E
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Bmp2 expression starts to be detected in the interdigital area. Bmp2 is expressed in the future metacarpal region, the most distal mesenchyme and the AER in the forelimb.
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Specimen
4F:
embryonic day 11.5; Dbf/Dbf +
(more )
Specimen
4F:
(close )
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Genetic Background:
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involves: 101/H * C3H/HeH
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Mutant Allele(s):
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Dbf/Dbf+
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: forelimb bud |
Present |
Regionally restricted |
4F
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In Dbf heterozygous mutants, ectopic Bmp2 expression is detected in a broad band across the AP axis at the distal part of both the forelimb and hindlimb.
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| TS19: handplate |
Present |
Regionally restricted |
4F
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Bmp2 expression can still be detected in a band-like domain in the anterior distal limb bud, where extra limb bud outgrowth is obvious and expression in the metacarpal region is narrows and extends to both the anterior and posterior ends as a thin band.
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Specimen
4G:
embryonic day 11.5
(more )
Specimen
4G:
(close )
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Genetic Background:
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involves: 101/H * C3H/HeH
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: footplate |
Present |
Regionally restricted |
4G
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Bmp2 expression can be detected in the metacarpal region of the hindlimb. Bmp2 expression is detected in the posterior-distal limb around the ZPA.
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| TS19: hindlimb bud |
Present |
Regionally restricted |
4G
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Bmp2 expression can be detected in the posterior-proximal limb margin.
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Specimen
4H:
embryonic day 11.5; Dbf/Dbf +
(more )
Specimen
4H:
(close )
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Genetic Background:
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involves: 101/H * C3H/HeH
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Mutant Allele(s):
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Dbf/Dbf+
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: hindlimb bud |
Present |
Regionally restricted |
4H
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In Dbf heterozygous mutants, ectopic Bmp2 expression is detected in a broad band across the AP axis at the distal part of both the forelimb and hindlimb.
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Specimen
4I:
embryonic day 12.5
(more )
Specimen
4I:
(close )
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Genetic Background:
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involves: 101/H * C3H/HeH
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
4J:
embryonic day 12.5; Dbf/Dbf +
(more )
Specimen
4J:
(close )
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Genetic Background:
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involves: 101/H * C3H/HeH
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Mutant Allele(s):
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Dbf/Dbf+
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
4K:
embryonic day 12.5
(more )
Specimen
4K:
(close )
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Genetic Background:
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involves: 101/H * C3H/HeH
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
4L:
embryonic day 12.5; Dbf/Dbf +
(more )
Specimen
4L:
(close )
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Genetic Background:
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involves: 101/H * C3H/HeH
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Mutant Allele(s):
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Dbf/Dbf+
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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whole mount
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