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Gene Expression Data
Assay Details
Assay
Reference: J:49322 Zuniga A, et al., Gli3 (Xt) and formin (ld) participate in the positioning of the polarising region and control of posterior limb-bud identity. Development. 1999 Jan;126(1):13-21
Assay type: RNA in situ
MGI Accession ID: MGI:1314732
Gene symbol: Hoxd11
Gene name: homeobox D11
Probe: Hoxd11 probe2
Probe preparation: labelled with digoxigenin RNA
Assay notes: All results were confirmed by also analyzing ld<In2>/Xt<H> intercrosses.
Results
Specimen 3a: embryonic day 9.75 (more )
Note: 28 somites.
Structure Level Pattern Image Note
TS15: forelimb bud Present Regionally restricted 3a Expression is posteriorly restricted.
Specimen 3b: embryonic day 9.75; Fmn1ld-Is(17;In2)1Gso/Fmn1ld-Is(17;In2)1Gso (more )
Note: 28 somites.
Structure Level Pattern Image Note
TS15: forelimb bud Present Regionally restricted 3b Expression is posteriorly restricted.
Specimen 3c: embryonic day 9.75; Gli3Xt-J/Gli3Xt-J (more )
Note: 28 somites.
Structure Level Pattern Image Note
TS15: forelimb bud Present Uniform 3c Posterior restriction of expression is lost.
Specimen 3d: embryonic day 9.75; Gli3Xt-J/Gli3Xt-J, Fmn1ld-Is(17;In2)1Gso/Fmn1ld-Is(17;In2)1Gso (more )
Note: 28 somites.
Structure Level Pattern Image Note
TS15: forelimb bud Present Uniform 3d Posterior restriction of expression is lost.
Specimen 4a: embryonic day 10.75 (more )
Note: 36-39 somites.
Structure Level Pattern Image Note
TS17: forelimb bud Present Regionally restricted 4a The wild-type forelimb bud shows the anterior expansion and distal restriction of the expression domain.
Specimen 4b: embryonic day 10.75; Fmn1ld-Is(17;In2)1Gso/Fmn1ld-Is(17;In2)1Gso (more )
Note: 36-39 somites.
Structure Level Pattern Image Note
TS17: forelimb bud Present Regionally restricted 4b ld/ld forelimb bud shows a delay in anterior expansion of the expression domain.
Specimen 4c: embryonic day 10.75; Gli3Xt-J/Gli3Xt-J (more )
Note: 36-39 somites.
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Present Regionally restricted 4c Expression restricts distally within the limb-bud mesenchymal core.
Specimen 4d: embryonic day 10.75; Gli3Xt-J/Gli3Xt-J, Fmn1ld-Is(17;In2)1Gso/Fmn1ld-Is(17;In2)1Gso (more )
Note: 36-39 somites.
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Present Regionally restricted 4d Significant expression remains proximal.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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