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Gene Expression Data
Assay Details
Assay
Reference: J:50306 Lakkis MM, et al., Neurofibromin modulation of ras activity is required for normal endocardial-mesenchymal transformation in the developing heart. Development. 1998 Nov;125(22):4359-67
Assay type: RNA in situ
MGI Accession ID: MGI:1303287
Gene symbol: Nrg1
Gene name: neuregulin 1
Probe: neuregulin probe1
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen +/+ heart: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: endocardial cushion Present Regionally restricted 3neuregulin +/+ Expression of neuregulin is confined to the endocardial cels of wild-type hearts.

Specimen -/- heart: embryonic day 13.5; Nf1tm1Tyj/Nf1tm1Tyj (more )
Structure Level Pattern Image Note
TS21: endocardial cushion Present Regionally restricted 3neuregulin -/- Expression of neuregulin extends into the mesenchymal portion of the cushion in Nf1-/- hearts.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory