Name ID |
B6.129S1(Cg)-Lrrc8atm1.1Geha MGI:5825471 |
Darker colors indicate more annotations |
Mouse Phenotypes | abnormal B cell differentiation |
abnormal T cell differentiation |
abnormal T cell physiology |
abnormal T cell selection |
abnormal thymus apoptosis |
abnormal thymus medulla morphology |
abnormal thymus morphology |
abnormal thymus physiology |
absent thymus corticomedullary boundary |
decreased B cell number |
decreased CD4-positive, alpha-beta T cell number |
decreased CD8-positive, alpha-beta T cell number |
decreased DN2 thymocyte number |
decreased DN3 thymocyte number |
decreased DN4 thymocyte number |
decreased double-negative T cell number |
decreased double-positive T cell number |
decreased immature B cell number |
decreased marginal zone B cell number |
decreased pre-B cell number |
decreased T cell number |
decreased T cell proliferation |
decreased thymocyte number |
decreased transitional stage B cell number |
increased IgG2a level |
increased pro-B cell number |
increased regulatory T cell number |
increased thymocyte apoptosis |
small spleen |
small thymus |
small thymus cortex |
thymus hypoplasia |
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Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||
Lrrc8atm1.1Geha/Lrrc8atm1.1Geha |