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B6.Cg-Tg(APP695)3Dbo Tg(PSEN1dE9)S9Dbo/Mmjax Strain Detail
Summary
  • Strain Name
    B6.Cg-Tg(APP695)3Dbo Tg(PSEN1dE9)S9Dbo/Mmjax
  • Attributes
    congenic, mutant strain, transgenic
  • MGI ID
    MGI:3619245
  • Synonyms
    APPswe line C3-3 x PS1dE9 line S-9, B6.Cg-Tg(APP695)3Dbo Tg(PSEN1dE9)S9Dbo/J
  • Other IDs
    JAX:005866, MMRRC:034833-JAX
Associated
Mutations,
Markers,
and QTL
2 associated mutations
Associated
Phenotypes
and
Diseases
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
normal phenotype
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Human Diseases

model 1
Alzheimer's disease 3 √
Key √ disease model expected model not found
Find Mice (IMSR)
1 associated strain record at IMSR
IMSR Repository IMSR Strain Why Matched
MMRRC:034833-JAX MMRRC B6J.Cg-Tg(APP695)3Dbo Tg(PSEN1dE9)S9Dbo/Mmjax exact match to ID
References
  • Earliest
    J:104236 Savonenko A, et al., Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: relationships to beta-amyloid deposition and neurotransmitter abnormalities. Neurobiol Dis. 2005 Apr;18(3):602-17
  • All
    3
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory