About   Help   FAQ
Sequence Detail
ID/Version
Q9Z0H7 Q3UBN4 (UniProt | EBI) Last sequence update: 1999-05-01
Last annotation update: 2024-03-27
Sequence
description
from provider
RecName: Full=B-cell lymphoma/leukemia 10;AltName: Full=B-cell CLL/lymphoma 10; Short=Bcl-10;AltName: Full=CARD-containing molecule enhancing NF-kappa-B;AltName: Full=CARD-like apoptotic protein {ECO:0000303|PubMed:10364242}; Short=mCLAP {
Provider SWISS-PROT
Sequence
Polypeptide 233 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Bcl10 B cell leukemia/lymphoma 10 124 100 3 12
Sequence references in MGI J:52071 Willis TG, et al., Bcl10 is involved in t(1;14)(p22;q32) of MALT B cell lymphoma and mutated in multiple tumor types. Cell. 1999 Jan 8;96(1):35-45
J:54311 Yan M, et al., mE10, a novel caspase recruitment domain-containing proapoptotic molecule. J Biol Chem. 1999 Apr 9;274(15):10287-92
J:54312 Koseki T, et al., CIPER, a novel NF kappaB-activating protein containing a caspase recruitment domain with homology to Herpesvirus-2 protein E10. J Biol Chem. 1999 Apr 9;274(15):9955-61
J:54313 Thome M, et al., Equine herpesvirus-2 E10 gene product, but not its cellular homologue, activates NF-kappaB transcription factor and c-Jun N-terminal kinase. J Biol Chem. 1999 Apr 9;274(15):9962-8
J:55630 Srinivasula SM, et al., CLAP, a novel caspase recruitment domain-containing protein in the tumor necrosis factor receptor pathway, regulates NF-kappaB activation and apoptosis. J Biol Chem. 1999 Jun 18;274(25):17946-54
J:92393 Liu Y, et al., BCL10 mediates lipopolysaccharide/toll-like receptor-4 signaling through interaction with Pellino2. J Biol Chem. 2004 Sep 3;279(36):37436-44
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:181290 Strasser D, et al., Syk kinase-coupled C-type lectin receptors engage protein kinase C-sigma to elicit Card9 adaptor-mediated innate immunity. Immunity. 2012 Jan 27;36(1):32-42
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory