Sequence Detail

ID/Version

Q9R0Y1 (UniProt | EBI)

Last sequence update: 2000-05-01
Last annotation update: 2025-04-09

Sequence description from provider

RecName: Full=Bile acid-sensitive ion channel {ECO:0000303|PubMed:22735174}; Short=BASIC {ECO:0000303|PubMed:22735174};AltName: Full=Acid-sensing ion channel subunit family member 5 {ECO:0000312|MGI:MGI:1929259};AltName: Full=Amiloride-sensitive c

Provider

SWISS-PROT

Sequence

Polypeptide 495 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Asic5	acid-sensing ion channel family member 5	40	97	2	12

Sequence references in MGI

J:66332 Sakai H, et al., Cloning and functional expression of a novel degenerin-like Na+ channel gene in mammals. J Physiol. 1999 Sep 1;519 Pt 2:323-33
J:166385 Wiemuth D, et al., A single amino acid tunes Ca2+ inhibition of brain liver intestine Na+ channel (BLINaC). J Biol Chem. 2010 Oct 1;285(40):30404-10
J:215064 Boiko N, et al., Restrictive expression of acid-sensing ion channel 5 (asic5) in unipolar brush cells of the vestibulocerebellum. PLoS One. 2014;9(3):e91326
J:287197 Kreko-Pierce T, et al., Cerebellar Ataxia Caused by Type II Unipolar Brush Cell Dysfunction in the Asic5 Knockout Mouse. Sci Rep. 2020 Feb 7;10(1):2168
J:359817 Wiemuth D, et al., BASIC--a bile acid-sensitive ion channel highly expressed in bile ducts. FASEB J. 2012 Oct;26(10):4122-30