Sequence Detail

ID/Version

Q9R0H0 O35616 A2A850 Q8BYC3 Q3TDG0 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Peroxisomal acyl-coenzyme A oxidase 1; Short=AOX; EC=1.3.3.6 {ECO:0000305|PubMed:11855929, ECO:0000305|PubMed:20195242};AltName: Full=Palmitoyl-CoA oxidase {ECO:0000250|UniProtKB:Q15067};AltName: Full=Peroxisomal fatty acyl-C

Provider

SWISS-PROT

Sequence

Polypeptide 661 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Acox1	acyl-Coenzyme A oxidase 1, palmitoyl	50	125	3	9

Sequence references in MGI

J:60554 Nohammer C, et al., cDNA cloning and analysis of tissue-specific expression of mouse peroxisomal straight-chain acyl-CoA oxidase. Eur J Biochem. 2000 Feb;267(4):1254-60
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:101653 Infante JP, et al., Straight-chain acyl-CoA oxidase knockout mouse accumulates extremely long chain fatty acids from alpha-linolenic acid: evidence for runaway carousel-type enzyme kinetics in peroxisomal beta-oxidation diseases. Mol Genet Metab. 2002 Feb;75(2):108-19
J:159333 Vluggens A, et al., Functional significance of the two ACOX1 isoforms and their crosstalks with PPARalpha and RXRalpha. Lab Invest. 2010 May;90(5):696-708
J:196142 Rardin MJ, et al., Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89