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Sequence Detail
Q9QZZ4 Q9QWL6 Q7TMR5 A2A637 A2A638 Q5SX93 O70395 Q7TMR6 (UniProt | EBI) Last sequence update: 2007-12-04
Last annotation update: 2023-05-03
from provider
RecName: Full=Unconventional myosin-XV;AltName: Full=Unconventional myosin-15;
Polypeptide 3511 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Myo15a myosin XVA 26 111 4 17
Sequence references in MGI J:48001 Probst FJ, et al., Correction of deafness in shaker-2 mice by an unconventional myosin in a BAC transgene [see comments]. Science. 1998 May 29;280(5368):1444-7
J:49063 Wakabayashi Y, et al., A novel type of myosin encoded by the mouse deafness gene shaker-2. Biochem Biophys Res Commun. 1998 Jul 30;248(3):655-9
J:58614 Liang Y, et al., Characterization of the human and mouse unconventional myosin XV genes responsible for hereditary deafness DFNB3 and shaker 2. Genomics. 1999 Nov 1;61(3):243-58
J:92621 Belyantseva IA, et al., Myosin XVa localizes to the tips of inner ear sensory cell stereocilia and is essential for staircase formation of the hair bundle. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):13958-63
J:102099 Belyantseva IA, et al., Myosin-XVa is required for tip localization of whirlin and differential elongation of hair-cell stereocilia. Nat Cell Biol. 2005 Feb;7(2):148-56
J:171832 Manor U, et al., Regulation of stereocilia length by myosin XVa and whirlin depends on the actin-regulatory protein Eps8. Curr Biol. 2011 Jan 25;21(2):167-72

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
The Jackson Laboratory