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Sequence Detail
ID/Version
Q9QZK2 Q3UP10 Q3TNC9 (UniProt | EBI) Last sequence update: 2000-05-01
Last annotation update: 2024-03-27
Sequence
description
from provider
RecName: Full=Breast cancer anti-estrogen resistance protein 3 homolog;AltName: Full=p130Cas-binding protein AND-34;
Provider SWISS-PROT
Sequence
Polypeptide 820 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Bcar3 breast cancer anti-estrogen resistance 3 25 102 3 30
Sequence references in MGI J:56740 Cai D, et al., AND-34, a novel p130Cas-binding thymic stromal cell protein regulated by adhesion and inflammatory cytokines. J Immunol. 1999 Aug 15;163(4):2104-12
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:152504 Near RI, et al., Loss of AND-34/BCAR3 expression in mice results in rupture of the adult lens. Mol Vis. 2009;15:685-99
J:168934 Garron ML, et al., Structural insights into the association between BCAR3 and Cas family members, an atypical complex implicated in anti-oestrogen resistance. J Mol Biol. 2009 Feb 13;386(1):190-203
J:188792 Sun G, et al., Protein tyrosine phosphatase alpha phosphotyrosyl-789 binds BCAR3 to position Cas for activation at integrin-mediated focal adhesions. Mol Cell Biol. 2012 Sep;32(18):3776-89
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory