Sequence Detail

ID/Version

Q9JM54 (UniProt | EBI)

Last sequence update: 2000-10-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Phorbol-12-myristate-13-acetate-induced protein 1;AltName: Full=Protein Noxa;

Provider

SWISS-PROT

Sequence

Polypeptide 103 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	47	116	2	6

Sequence references in MGI

J:62057 Oda E, et al., Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science. 2000 May 12;288(5468):1053-8
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:110228 Akhtar RS, et al., BH3-only proapoptotic Bcl-2 family members Noxa and Puma mediate neural precursor cell death. J Neurosci. 2006 Jul 5;26(27):7257-64
J:114705 Chen L, et al., Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function. Mol Cell. 2005 Feb 4;17(3):393-403
J:114727 Willis SN, et al., Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins. Genes Dev. 2005 Jun 1;19(11):1294-305
J:248256 Czabotar PE, et al., Structural insights into the degradation of Mcl-1 induced by BH3 domains. Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6217-22