Sequence Detail

ID/Version

Q9EST8 Q3URP0 Q3U8Y9 Q3UCI2 Q99NA4 Q3TWK9 Q3UW99 Q3TVL7 Q5NT97 (UniProt | EBI)

Last sequence update: 2001-03-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=NF-kappa-B inhibitor zeta;AltName: Full=I-kappa-B-zeta; Short=IkB-zeta; Short=IkappaBzeta;AltName: Full=IL-1 inducible nuclear ankyrin-repeat protein; Short=INAP;AltName: Full=Molecule possessing ankyrin repeats induc

Provider

SWISS-PROT

Sequence

Polypeptide 728 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta	98	101	3	10

Sequence references in MGI

J:65974 Kitamura H, et al., MAIL, a novel nuclear IkappaB protein that potentiates LPS-induced IL-6 production. FEBS Lett. 2000 Nov 17;485(1):53-6
J:73827 Shiina T, et al., Genomic organization, chromosomal localization, and promoter analysis of the mouse Mail gene. Immunogenetics. 2001 Oct;53(8):649-55
J:91297 Yamamoto M, et al., Regulation of Toll/IL-1-receptor-mediated gene expression by the inducible nuclear protein IkappaBzeta. Nature. 2004 Jul 8;430(6996):218-22
J:97246 Motoyama M, et al., Positive and negative regulation of nuclear factor-kappaB-mediated transcription by IkappaB-zeta, an inducible nuclear protein. J Biol Chem. 2005 Mar 4;280(9):7444-51
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:216064 Tartey S, et al., Akirin2 is critical for inducing inflammatory genes by bridging IkappaB-zeta and the SWI/SNF complex. EMBO J. 2014 Oct 16;33(20):2332-48
J:259145 Jeltsch KM, et al., Cleavage of roquin and regnase-1 by the paracaspase MALT1 releases their cooperatively repressed targets to promote T(H)17 differentiation. Nat Immunol. 2014 Nov;15(11):1079-89