Sequence Detail

ID/Version

Q9ES28 Q91ZZ6 Q6XPA5 Q9ES27 Q3UTS5 Q8C750 Q6ZQI5 O08757 (UniProt | EBI)

Last sequence update: 2007-02-06
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Rho guanine nucleotide exchange factor 7;AltName: Full=Beta-Pix;AltName: Full=PAK-interacting exchange factor beta;AltName: Full=p85SPR;

Provider

SWISS-PROT

Sequence

Polypeptide 862 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Arhgef7	Rho guanine nucleotide exchange factor	59	104	4	17

Sequence references in MGI

J:56615 Bagrodia S, et al., A tyrosine-phosphorylated protein that binds to an important regulatory region on the cool family of p21-activated kinase-binding proteins. J Biol Chem. 1999 Aug 6;274(32):22393-400
J:62793 Kim S, et al., Molecular cloning of neuronally expressed mouse betaPix isoforms. Biochem Biophys Res Commun. 2000 Jun 16;272(3):721-5
J:63104 Oh WK, et al., Cloning of a SH3 domain-containing proline-rich protein, p85SPR, and its localization in focal adhesion. Biochem Biophys Res Commun. 1997 Jun 27;235(3):794-8
J:86686 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Aug 31;10(4):167-80
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:121008 Chang F, et al., FAK potentiates Rac1 activation and localization to matrix adhesion sites: a role for betaPIX. Mol Biol Cell. 2007 Jan;18(1):253-64
J:141061 Angrand PO, et al., Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling. Mol Cell Proteomics. 2006 Dec;5(12):2211-27
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:187362 Munton RP, et al., Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. Mol Cell Proteomics. 2007 Feb;6(2):283-93
J:189982 Matsuda C, et al., Affixin activates Rac1 via betaPIX in C2C12 myoblast. FEBS Lett. 2008 Apr 9;582(8):1189-96
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89