Sequence Detail

ID/Version

Q9DBR0 Q9R0L8 (UniProt | EBI)

Last sequence update: 2001-06-01
Last annotation update: 2026-06-10

Sequence description from provider

RecName: Full=A-kinase anchor protein 8; Short=AKAP-8;AltName: Full=A-kinase anchor protein 95 kDa; Short=AKAP 95;

Provider

SWISS-PROT

Sequence

Polypeptide 687 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Akap8	A kinase anchor protein 8	47	102	2	35

Sequence references in MGI

J:94339 Bomar J, et al., Differential regulation of maternal and paternal chromosome condensation in mitotic zygotes. J Cell Sci. 2002 Jul 15;115(Pt 14):2931-40
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:116474 Yang Y, et al., Interaction between fidgetin and protein kinase A-anchoring protein AKAP95 is critical for palatogenesis in the mouse. J Biol Chem. 2006 Aug 4;281(31):22352-9
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:230622 Wall EA, et al., Suppression of LPS-induced TNF-alpha production in macrophages by cAMP is mediated by PKA-AKAP95-p105. Sci Signal. 2009;2(75):ra28
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:306378 Guo A, et al., Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics. 2014 Jan;13(1):372-87
J:383262 Arsenijevic T, et al., A novel partner for D-type cyclins: protein kinase A-anchoring protein AKAP95. Biochem J. 2004 Mar 1;378(Pt 2):673-9
J:385167 Furusawa M, et al., AMY-1 interacts with S-AKAP84 and AKAP95 in the cytoplasm and the nucleus, respectively, and inhibits cAMP-dependent protein kinase activity by preventing binding of its catalytic subunit to A-kinase-anchoring protein (AKAP) complex. J Biol Chem. 2002 Dec 27;277(52):50885-92