Sequence Detail

ID/Version

Q9DAU7 (UniProt | EBI)

Last sequence update: 2001-06-01
Last annotation update: 2026-06-10

Sequence description from provider

RecName: Full=WAP four-disulfide core domain protein 2 {ECO:0000312|MGI:MGI:1914951};AltName: Full=WAP domain-containing protein HE4;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 174 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Wfdc2	WAP four-disulfide core domain 2	13	102	3	14

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:282576 Nakajima K, et al., Lack of whey acidic protein (WAP) four-disulfide core domain protease inhibitor 2 (WFDC2) causes neonatal death from respiratory failure in mice. Dis Model Mech. 2019 Nov 12;12(11):dmm040139
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:293623 Zhang T, et al., WFDC2 gene deletion in mouse led to severe dyspnea and type-I alveolar cell apoptosis. Biochem Biophys Res Commun. 2020 Feb 5;522(2):456-462