Sequence Detail

ID/Version

Q9CR14 Q3TGY2 Q9D017 (UniProt | EBI)

Last sequence update: 2001-06-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=E3 ubiquitin-protein ligase FANCL; EC=2.3.2.27 {ECO:0000250|UniProtKB:Q9NW38};AltName: Full=Fanconi anemia group L protein homolog;AltName: Full=Proliferation of germ cells protein;AltName: Full=RING-type E3 ubiquitin transferase FAN

Provider

SWISS-PROT

Sequence

Polypeptide 375 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fancl	Fanconi anemia, complementation group L	32	102	3	14

Sequence references in MGI

J:80424 Agoulnik AI, et al., A novel gene, Pog, is necessary for primordial germ cell proliferation in the mouse and underlies the germ cell deficient mutation, gcd. Hum Mol Genet. 2002 Nov 15;11(24):3047-53
J:84032 Lu B, et al., Late onset of spermatogenesis and gain of fertility in POG-deficient mice indicate that POG is not necessary for the proliferation of spermatogonia. Biol Reprod. 2003 Jul;69(1):161-8
J:84438 Lu B, et al., Mouse GGN1 and GGN3, two germ cell-specific proteins from the single gene Ggn, interact with mouse POG and play a role in spermatogenesis. J Biol Chem. 2003 May 2;278(18):16289-96
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:178431 Zhang Y, et al., UBE2W interacts with FANCL and regulates the monoubiquitination of Fanconi anemia protein FANCD2. Mol Cells. 2011 Feb;31(2):113-22