Sequence Detail

ID/Version

Q99P68 Q9D3L7 B2RQA5 (UniProt | EBI)

Last sequence update: 2019-04-10
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Sclerostin {ECO:0000303|PubMed:15778503};Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 211 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Sost	sclerostin	36	118	3	24

Sequence references in MGI

J:67858 Brunkow M, et al., Bone dysplasia sclerosteosis results from loss of the sost gene product, a novel cystine knot-containing protein. Am J Hum Genet. 2001 Mar;68(3):577-89
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:168665 Lin C, et al., Sclerostin mediates bone response to mechanical unloading through antagonizing Wnt/beta-catenin signaling. J Bone Miner Res. 2009 Oct;24(10):1651-61