Sequence Detail

ID/Version

Q99ML8 F8WIL4 (UniProt | EBI)

Last sequence update: 2013-09-18
Last annotation update: 2026-06-10

Sequence description from provider

RecName: Full=Urocortin-2;AltName: Full=Urocortin II {ECO:0000303|PubMed:11226328}; Short=Ucn II {ECO:0000303|PubMed:11226328};Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 113 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ucn2	urocortin 2	32	96	3	3

Sequence references in MGI

J:67860 Reyes TM, et al., Urocortin II: a member of the corticotropin-releasing factor (CRF) neuropeptide family that is selectively bound by type 2 CRF receptors. Proc Natl Acad Sci U S A. 2001 Feb 27;98(5):2843-8
J:116101 Chen A, et al., Urocortin 2 modulates glucose utilization and insulin sensitivity in skeletal muscle. Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16580-5
J:132850 Hao Z, et al., Urocortin2 inhibits tumor growth via effects on vascularization and cell proliferation. Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3939-44
J:166245 Neufeld-Cohen A, et al., A triple urocortin knockout mouse model reveals an essential role for urocortins in stress recovery. Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):19020-5
J:383051 Vaughan JM, et al., Posttranslational processing of human and mouse urocortin 2: characterization and bioactivity of gene products. Endocrinology. 2013 Apr;154(4):1553-64