Sequence Detail

ID/Version

Q925G2 A2AUU8 Q9D7U1 (UniProt | EBI)

Last sequence update: 2008-01-15
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Plasma membrane ascorbate-dependent reductase CYBRD1 {ECO:0000250|UniProtKB:Q53TN4}; EC=7.2.1.3 {ECO:0000250|UniProtKB:Q53TN4};AltName: Full=Cytochrome b reductase 1;AltName: Full=Duodenal cytochrome b {ECO:0000303|PubMed:12547225};

Provider

SWISS-PROT

Sequence

Polypeptide 290 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cybrd1	cytochrome b reductase 1	25	102	3	7

Sequence references in MGI

J:80404 Dupic F, et al., Duodenal mRNA expression of iron related genes in response to iron loading and iron deficiency in four strains of mice. Gut. 2002 Nov;51(5):648-53
J:82711 McKie AT, et al., An iron-regulated ferric reductase associated with the absorption of dietary iron. Science. 2001 Mar 2;291(5509):1755-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:108980 Muckenthaler M, et al., Regulatory defects in liver and intestine implicate abnormal hepcidin and Cybrd1 expression in mouse hemochromatosis. Nat Genet. 2003 May;34(1):102-7
J:117705 Su D, et al., Human erythrocyte membranes contain a cytochrome b561 that may be involved in extracellular ascorbate recycling. J Biol Chem. 2006 Dec 29;281(52):39852-9
J:119528 Gunshin H, et al., Cybrd1 (duodenal cytochrome b) is not necessary for dietary iron absorption in mice. Blood. 2005 Oct 15;106(8):2879-83